溶解性 | Soluble in water (<1 mg/ml at 25 °C), DMSO (83 mg/ml at 25 °C), methanol, Aqueous Alkali, and ethanol (83 mg/ml at 25 °C). |
存贮条件 | 储存温度 2-8°C |
应用 | An inhibitor of the angiotensin- coverting enzyme (ACE). |
产品介绍 | Ramipril 是血管紧张素转换酶(ACE)抑制剂,IC50为5 nM。 |
备注 | Ramipril (Altace) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM. |
生化机理 | Ramipril is an inhibitor of the ACE (angiotensin- converting enzyme) that is reported to quickly hydrolyze into the active metabolite Ramiprilat. Studies indicate that Ramipril is a more potent inhibitor in comparison to Zofenopril. Acute coronary syndrome investigations demonstrate that Ramipril increases IL-10, and decreases the levels of MCP-1 and IL-18. |
别名 | 雷米普利; N-[1(S)-乙氧羰基-3-苯丙基]-(S)-丙氨酰基-顺桥-2-氮杂二环[3,3,0]辛烷-3(S)-羧酸;(2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-(乙氧羰基)-3-苯丙基]氨基]-1-氧代丙基]八氢环戊并[b]吡咯-2-羧酸;Tritace;[2S,3aS,6aS]-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid |
雷米普利
Ramipril (订货以英文为准)
编号:R129247
CAS号:87333-19-5
分子式:C23H32N2O5
分子量:416.51
产品名称 | Ramipril |
中文名称 | 雷米普利 |
CAS号 | 87333-19-5 |
分子式(M.F.) | C23H32N2O5 |
分子量(M.W.) | 416.51 |
储存条件 | 2-8°C储存 |
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