依那普利拉 二水合物

Enalaprilat Dihydrate (订货以英文为准)

编号:E129224
CAS号:84680-54-6
分子式:C18H24N2O5.2H2O
分子量:348.42
货号 品牌 包装 目录价 您的价格 库存 数量 购买
E129224-50mg 阿拉丁 50mg ¥355.90
E129224-100mg 阿拉丁 100mg ¥521.90
E129224-250mg 阿拉丁 250mg ¥766.90
产品名称 Enalaprilat Dihydrate
中文名称 依那普利拉 二水合物
CAS号 84680-54-6
分子式(M.F.) C18H24N2O5.2H2O
分子量(M.W.) 348.42
储存条件 2-8°C储存
熔点151-159 °C
溶解性Soluble in water (5 mg/ml at 25 °C), ethanol (1 mg/ml at 25 °C), DMSO (70 mg/ml at 25 °C), methanol, and DMF.
存贮条件储存温度 2-8°C
应用An active metabolite of the ACE inhibitor, Enalapril.
产品介绍Enalaprilat Dihydrate是一种新型血管紧张肽转化酶(ACE)抑制剂,IC50为1.2 nM。
备注Enalaprilat is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM.
生化机理Enaprilat is the active metabolite of the compound Enalapril. Enalapril is an ACE (angiotensin-converting enzyme) inhibitor, suggested to be more potent than Captopril. The compound is reported to be converted to the active form, Enalaprilat , through hepatic hydrolysis. Enalapril downregulates the expression of IL-β, IL-6, and NK-κB. Enalaprilat dihydrate is an activator of bradykinin B1 R.
别名依那普利拉二水合物;2,4-二氯苯基-2-(-1H-咪唑)乙醇;(2S)-1-[(2S)-2-[[(1S)-1-Carboxy-3-phenyl-propyl]amino]propanoyl]pyrrolidine-2-carboxylic acid;Vasotec;Enalapril
WGK德国3
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