| 熔点 | 223-224 °C |
| 溶解性 | Soluble in DMSO (10 mg/ml), DMF (5 mg/ml), 1:1 DMSO:PBS(pH 7.2) (~1 mg/ml), and ethanol (≥1 mg/ml). Insoluble in water. |
| 存贮条件 | 储存温度 2-8°C |
| 应用 | A potent and selective thromboxane A2 inhibitor. |
| 产品介绍 | Ozagrel是一种有效的，选择性的血栓素A2合成酶抑制剂，IC50为4 nM。 |
| 备注 | Ozagrel is a potent and selective thromboxane A2 synthetase inhibitor with an IC50 of 4 nM. |
| 生化机理 | Ozagrel, an antithrombic drug, is a potent and selective TXA Synthase (thromboxane A2) inhibitor highly active in human platelets. Found to induce apoptosis in T24 and TCC-SUP bladder cancer cells. Ozagrel improved locomotor activity and coordination in ischemia-reperfusion injured mice models and has potential therapeutic usage for stroke. Reported to inhibit pulmonary thromboxane B2 delivery blocking the increase in systemic vascular resistance. Also shown to inhibit phenolase activities of mushroom tyrosinase. |
| 别名 | 奥扎格雷; 反式-3-[4-(1H-咪唑-1-基甲基)苯基]-2-丙烯酸;OKY046; OKY-046; OKY 046;(E)-3-[4-(1H-Imidiazol-1-ylmethyl)phenyl]-2-propenic acid |
奥扎格雷
Ozagrel （订货以英文为准）
编号：O129871
CAS号：82571-53-7
分子式：C13H12N2O2
分子量：228.25
| 产品名称 | Ozagrel |
| 中文名称 | 奥扎格雷 |
| CAS号 | 82571-53-7 |
| 分子式（M.F.） | C13H12N2O2 |
| 分子量（M.W.） | 228.25 |
| 储存条件 | 2-8°C储存 |
| RTECS | FG1602400 |
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