溶解性 | 78 mg/mL in DMSO <1 mg/mL in Water 78 mg/mL in Ethanol |
存贮条件 | 储存温度-20°C |
应用 | A CETP inhibitor |
产品介绍 | Dalcetrapib (JTT-705, RO4607381)是一种rhCETP抑制剂,IC50为0.2 μM,提高血浆中高密度脂蛋白(HDL)胆固醇。 |
备注 | Dalcetrapib (JTT-705) is a rhCETP inhibitor with IC50 of 0.2 μM that increases the plasma HDL cholesterol. Phase 3. |
生化机理 | Dalcetrapib is a CETP inhibitor for rhCETP with IC50 of 0.2 μM |
别名 | 达塞曲匹; CETP 抑制剂;JTT-705;RO-4607381;JTT705;JTT 705;RO 4607381;RO4607381;2-Methylpropanethioic acid S-[2-[1-(2-ethylbutyl)cyclohexylcarboxamido]phenyl] ester |
达塞曲匹
Dalcetrapib (订货以英文为准)
编号:D125851
CAS号:211513-37-0
分子式:C23H35NO2S
分子量:389.59
产品名称 | Dalcetrapib |
中文名称 | 达塞曲匹 |
CAS号 | 211513-37-0 |
分子式(M.F.) | C23H35NO2S |
分子量(M.W.) | 389.59 |
储存条件 | -20°C储存 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs02.jpg,https://www.aladdin-e.com/images/ghs/ghs07.jpg |
信号词 | Danger |
危害声明 | H225-H302 + H332-H319 |
警示性声明 | P210-P305 + P351 + P338 |
RTECS | UQ4431050 |
WGK德国 | 2 |
闪点(摄氏) | 35.6 °F |
技术规格
Background: | Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle. |
Applications: | ELISA, IHC |
Name of antibody: | UBAC1 |
Immunogen: | Fusion protein of human UBAC1 |
Full name: | UBA domain containing 1 |
Synonyms: | KPC2; GBDR1; UBADC1 |
SwissProt: | Q9BSL1 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human tonsil and Human colorectal cancer |
IHC Recommend dilution: | 50-300 |
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