小鼠抗PDHA1单克隆抗体
产品编号：D190628
品牌：BBI
产品特点：
| 货号 | 包装 | 规格 | 目录价 | 您的价格 | 库存 | 数量 | 购买 |
|---|---|---|---|---|---|---|---|
| D190628-0100 | 100ul | ¥2000.00 |
|
技术规格
| Background: | The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Applications: | WB, IF |
| Name of antibody: | PDHA1 |
| Immunogen: | Fusion protein of human PDHA1 |
| Full name: | pyruvate dehydrogenase E1 alpha 1 subunit |
| Synonyms: | PDHA; PDHAD; PHE1A; PDHCE1A |
| SwissProt: | P08559 |
| WB Predicted band size: | 43 kDa |
| WB Positive control: | 293, 1299, mEsc and Tc1 cell lysates |
| WB Recommended dilution: | 1000-5000 |
| IF positive control: | Hela cells |
| IF Recommend dilution: | 50-100 |
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