沸点 | 116 °C |
熔点 | -75℃ |
折光率 | 1.4290 |
密度 | 0.7400 |
别名 | ; |
2,5-二甲基-1,5-己二烯
2,5-Dimethyl-1,5-hexadiene (订货以英文为准)
编号:D155280
CAS号:627-58-7
分子式:C8H14
分子量:110.20
产品名称 | 2,5-Dimethyl-1,5-hexadiene |
中文名称 | 2,5-二甲基-1,5-己二烯 |
CAS号 | 627-58-7 |
分子式(M.F.) | C8H14 |
分子量(M.W.) | 110.20 |
RTECS | EM4264000 |
闪点(摄氏) | -19°C |
是否危化品 | 一般危化品 |
技术规格
Background: | Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex act via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. Compared to RNF2/RING2, it does not have the main E3 ubiquitin ligase activity on histone H2A, and it may rather act as a modulator of RNF2/RING2 activity. |
Applications: | WB |
Name of antibody: | RING1 |
Immunogen: | Synthetic peptide of human RING1 |
Full name: | ring finger protein 1 |
Synonyms: | RNF1; RING1A |
SwissProt: | Q06587 |
WB Predicted band size: | 42 kDa |
WB Positive control: | Hela cells |
WB Recommended dilution: | 500-1000 |
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