小鼠抗CHD3(C-term)单克隆抗体

产品编号:D190641 品牌:BBI
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D190641-0100 100ul ¥2000.00

技术规格

Background: This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Applications: WB, IF, IP
Name of antibody: CHD3(C-term)
Immunogen: Fusion protein of human CHD3
Full name: chromodomain helicase DNA binding protein 3
Synonyms: ZFH; Mi-2a; Mi2-ALPHA
SwissProt: Q12873
WB Predicted band size: 227 kDa
WB Positive control: NTERA2, 3T3, C6, K562 and Hela cell lysates
WB Recommended dilution: 1000-5000
IF positive control: Hela cells
IF Recommend dilution: 200-400
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