| 溶解性 | Soluble in water (<1 mg/ml at 25 °C), chloroform, methanol, DMSO (91 mg/ml at 25 °C), and ethanol (91 mg/ml at 25 °C). |
| 存贮条件 | 储存温度2-8℃ |
| 应用 | A KIR6 (KATP) channel blocker |
| 产品介绍 | Repaglinide用于治疗II型糖尿病。 |
| 备注 | Repaglinide is for the treatment of type II diabetes. |
| 生化机理 | Repaglinide is a KIR6 (KATP) channel blocker that binds with high affinity for SUR1 when co-expressed with KIR6.2(Kd = 0.42 nM).Repaglinide is a potent short-acting insulin secretagogue that acts by closing ATP-sensitive potassium (KATP) channels in the plasma membrane of the pancreatic beta cell. It represents a new class of insulin secretagogues, structurally unrelated to sulphonylureas, which were developed for the treatment of type 2 diabetes. |
| 别名 | Prandin, GlucoNorm, NovoNorm;瑞格列奈; (S)-2-乙氧基-4-[2-[3-甲基-1-[2-(1-哌啶基)苯基]-丁烷基]-氨基]-2-羰乙基苯甲酸;(S)-(+)-2-Ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]aminocarbonylmethyl]benzoic acid; Novonorm; Prandin |
瑞格列奈
Repaglinide （订货以英文为准）
编号：R129561
CAS号：135062-02-1
分子式：C27H36N2O4
分子量：452.59
| 产品名称 | Repaglinide |
| 中文名称 | 瑞格列奈 |
| CAS号 | 135062-02-1 |
| MDL编码 | MFCD00906179 |
| 分子式（M.F.） | C27H36N2O4 |
| 分子量（M.W.） | 452.59 |
| 储存条件 | 2-8°C储存 |
| Reaxys-RN | 3572609 |
| 信号词 | Warning |
| 危害声明 | H302 |
| RTECS | US7968300 |
| WGK德国 | 3 |
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