3,6-二溴-9-乙基咔唑

3,6-Dibromo-9-ethylcarbazole (订货以英文为准)

编号:D121519
CAS号:33255-13-9
分子式:C14H11BR2N
分子量:353.05
货号 品牌 包装 目录价 您的价格 库存 数量 购买
D121519-5g 阿拉丁 5g ¥831.90
D121519-1g 阿拉丁 1g ¥189.90
D121519-25g 阿拉丁 25g ¥3233.90
产品名称 3,6-Dibromo-9-ethylcarbazole
中文名称 3,6-二溴-9-乙基咔唑
CAS号 33255-13-9
MDL编码 MFCD00138134
分子式(M.F.) C14H11BR2N
分子量(M.W.) 353.05
别名;
WGK德国3

技术规格

Background: Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced transcript variants have been described.
Applications: ELISA, IHC
Name of antibody: ADD2
Immunogen: Fusion protein of human ADD2
Full name: adducin 2 (beta)
Synonyms: ADDB
SwissProt: P35612
ELISA Recommended dilution: 1000-2000
IHC positive control: Human brain
IHC Recommend dilution: 15-50
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搜索MSDS
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