存贮条件 | 储存温度2-8℃ |
应用 | A protease that cleaves proteins on the carboxyl bond of arginine |
产品介绍 | Clostripain (Endoproteinase-Arg-C) is a two chain proteinase associated with collagenase and isolated from Clostridium histolyticum. It is highly specific for the carboxyl peptide bond of arginine. Clostripain has a sulfhydryl requirement; it is activated by dithiothreitol, cysteine, or other sulfhydryl containing reagents. The presence of calcium ions is essential. The enzyme is inhibited by oxidizing agents and sulfhydryl reactants and by Co2+, Cu2+, Cd2+, and heavy metal ions. Citrate, borate, and Tris anions are less inhibitory. |
备注 | Chromatographically purified. A dialyzed, lyophilized pre-activated powder. |
生化机理 | Clostripain from Clostridium histolyticum is composed of two polypeptide chains, with molecular masses of 41.7 kDa and 15.4 kDa. Clostripain has a highly restricted substrate specificity for Arg-Xaa peptide bonds. Therefore, clostripain has been explored as a potential enzyme for protein sequencing purposes. It has also been studied as a catalyst for condensation of pharmaceutically important peptides containing Arg-Pro bonds. |
别名 | ;Endoproteinase-Arg-C;Clostridiopeptidase B;Proteinase from Clostridium histolyticum |
梭菌蛋白酶 来源于溶组织梭菌
Clostripain from Clostridium histolyticum (订货以英文为准)
编号:C128677
CAS号:9028-00-6
分子式:232-822-2
产品名称 | Clostripain from Clostridium histolyticum |
中文名称 | 梭菌蛋白酶 来源于溶组织梭菌 |
CAS号 | 9028-00-6 |
分子式(M.F.) | 232-822-2 |
储存条件 | 2-8°C储存 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg,https://www.aladdin-e.com/images/ghs/ghs08.jpg |
信号词 | Danger |
危害声明 | H315,H319,H334,H335 |
警示性声明 | P261,P305+P351+P338,P342+P311 |
个人防护设备 | Eyeshields, Gloves |
WGK德国 | 3 |
风险声明 (欧洲) | R36/37/38;R42 |
安全声明(欧洲) | S22;S24;S26;S36/37 |
危害码(欧洲) | Xn |
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