| 溶解性 | DMSO |
| 存贮条件 | 储存温度-20°C |
| 生化机理 | JDTic is a drug that acts as an opioid antagonist, which is highly selective for the κ-opioid receptor. JDTic blocks this receptor without affecting the μ- or δ-opioid receptors. JDTic is a 4-phenylpiperidine derivative, distantly structurally related to analgesic drugs such as meperidine and ketobemidone, and more closely to the mu opioid antagonist alvimopan, and is structurally distinct from other kappa antagonists such as norbinaltorphimine. JDTic has a very long duration of action, with effects in animals seen for up to several weeks after administration of a single dose, although its binding to the kappa opioid receptor is not irreversible and its long-acting effects are instead caused by altered activity of c-Jun N-terminal kinases. Animal studies suggest that it may produce antidepressant and anxiolytic effects, as well as having possible application in the treatment of addiction to cocaine and morphine. |
| 别名 | ; |
JDTic
JDTic （订货以英文为准）
编号：J125957
CAS号：361444-66-8
分子式：C28H39N3O3
分子量：465.63
| 产品名称 | JDTic |
| 中文名称 | JDTic |
| CAS号 | 361444-66-8 |
| 分子式（M.F.） | C28H39N3O3 |
| 分子量（M.W.） | 465.63 |
| 储存条件 | -20°C储存 |
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