熔点 | 165-166 °C |
溶解性 | Soluble in water (83 mg/ml), DMSO (83 mg/ml), and methanol (very slightly). Insoluble in ethanol, and ether |
存贮条件 | 储存温度 2-8°C |
应用 | A selective 5-HT1 receptor agonist. |
产品介绍 | Sumatriptan Succinate是一种含有磺酰胺基团的曲坦类磺胺类药物,用于治疗偏头痛。 |
备注 | Sumatriptan Succinate is a triptan sulfa drug containing a sulfonamide group for the treatment of migraine headaches. |
生化机理 | Sumatriptan succinate is a selective 5-HT1 receptor agonist with specificity towards 5-HT1D, 5-HT1B and 5-HT1A. In addition, the physicochemical properties of Sumatriptan succinate can be characterized using FT-IR, HPLC, SEM and XRD. It has been reported that Sumatriptan succinate can be produced via reactive precipitation without the presence of surfactants. Further studies show that molecules of Sumatriptan succinate are carried through cells using liposomes, with positively charged liposomes exhibiting the highest loading efficiency. |
别名 | 琥珀酸舒马坦;3-[2-(二甲氨基)乙基]-1H-吲哚-5-基-N-甲基磺酰甲胺琥珀酸盐;GR 43175; Imigran; Imitrex;3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate;Micralgin; Migratan |
琥珀酸舒马坦
3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate (订货以英文为准)
编号:S129681
CAS号:103628-48-4
分子式:C14H21N3O2S.C4H6O4
分子量:413.49
产品名称 | 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate |
中文名称 | 琥珀酸舒马坦 |
CAS号 | 103628-48-4 |
MDL编码 | MFCD00902856 |
分子式(M.F.) | C14H21N3O2S.C4H6O4 |
分子量(M.W.) | 413.49 |
储存条件 | 2-8°C储存 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg |
信号词 | Warning |
危害声明 | H302-H319 |
警示性声明 | P305 + P351 + P338 |
个人防护设备 | dust mask type N95 (US), Eyeshields, Gloves |
RTECS | UX9655650 |
WGK德国 | 3 |
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