3-氨基-1,2,4-三唑

3-Amino-1,2,4-triazole (订货以英文为准)

编号:A107201
CAS号:61-82-5
分子式:C2H4N4
分子量:84.08
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A107201-250mg 阿拉丁 250mg ¥944.90
产品名称 3-Amino-1,2,4-triazole
中文名称 3-氨基-1,2,4-三唑
CAS号 61-82-5
MDL编码 MFCD00005230
分子式(M.F.) C2H4N4
分子量(M.W.) 84.08
储存条件 -20°C储存
熔点149-156°C
溶解性Soluble in water (280 g/l) at 20 °C, methanol, ethanol, chloroform, and ethyl acetate (slightly). Insoluble in ether, and acetone.
密度1.1380
应用An irreversible catalase inhibitor
产品介绍3-Amino-1,2,4-triazole is a small molecule irreversible inhibitor of catalase, an enzyme responsible for converting cellular H2O2 into H2O and O2. Impeding the natural clearance of H2O2 from the cell by catalase has proven useful in studies investigating free radical-mediated damage of cardiac tissue in ischemia. 3-Amino-1,2,4-triazole also shows inhibition of imidazoleglycerol-phosphate dehydratase (HIS3) activity, which interrupts the biosynthesis of histidines. When 3-Amino-1,2,4-triazole is diazotized, the resulting 3-Diazo-1,2,4-triazole is shown to react specifically with tryptophan at acidic pH, presenting a method for determining the tryptophan content of proteins.
别名3-氨基-1,2,4-三氮唑;3-氨基-1,2,4-三氮杂茂;氨基三唑;杀草强Aminotriazole;Amitrol;3-Amino-1H-1,2,4-triazole
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