| 溶解性 | DMSO |
| 存贮条件 | 储存温度-20°C |
| 产品介绍 | NBD-557是HIV-1抑制剂。 |
| 生化机理 | NBD-557, is small molecule organic compounds with drug-like properties. It showed potent cell fusion and virus-cell fusion inhibitory activity at low micromolar levels. A systematic study showed that NBD-557 target viral entry by inhibiting the binding of HIV-1 envelope glycoprotein gp120 to the cellular receptor CD4 but did not inhibit reverse transcriptase, integrase, or protease, indicating that they do not target the later stages of the HIV-1 life cycle to inhibit HIV-1 infection. NBD-557 potent inhibitors of both X4 and R5 viruses tested in CXCR4 and CCR5 expressing cell lines, respectively, indicating that its anti-HIV-1 activity is not dependent on the coreceptor tropism of the virus. |
| 别名 | NBD 557;NBD557;N-(4-溴苯基)-N'-(2,2,6,6-四甲基哌啶-4-基)草酰胺;NBD 557;NBD557;N-(4-Bromophenyl)-N'-(2,2,6,6-tetramethylpiperidin-4-yl)oxalamide;N1-(4-bromophenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)ethanediamide |
NBD-557,HIV-1抑制剂
NBD-557 （订货以英文为准）
编号：N125473
CAS号：333352-59-3
分子式：C17H24BRN3O2
分子量：382.30
| 产品名称 | NBD-557 |
| 中文名称 | NBD-557,HIV-1抑制剂 |
| CAS号 | 333352-59-3 |
| 分子式（M.F.） | C17H24BRN3O2 |
| 分子量（M.W.） | 382.30 |
| 储存条件 | -20°C储存 |
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