熔点 | 137°C |
溶解性 | Soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), chloroform, and methanol. |
存贮条件 | 储存温度 2-8°C |
应用 | A peripheral histamine H1 receptor agonist. |
产品介绍 | Loratadine是一种选择性的,逆向外周组胺H1受体激动剂,IC50大于32 μM。 |
备注 | Loratadine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. |
生化机理 | Loratadine is a non-sedative antihistamine that inhibits histamine-induced activities of IL-6 and IL-8 secretion in endothelial cells. Loratadine is a selective inverse peripheral histamine H1-receptor agonist (IC50 > 32 μM). |
别名 | 克敏能;氯雷他定;4-(8-氯-5,6-二氢-11H-苯并[5,6]环庚基[1,2-b]并吡啶-11-烯)-1-哌啶羧酸乙脂;4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester;Loratidine;SCH 29851; SCH29851; SCH-29851 |
氯雷他定
Loratadine (订货以英文为准)
编号:L129223
CAS号:79794-75-5
分子式:C22H23CLN2O2
分子量:382.88
产品名称 | Loratadine |
中文名称 | 氯雷他定 |
CAS号 | 79794-75-5 |
MDL编码 | MFCD00672869 |
分子式(M.F.) | C22H23CLN2O2 |
分子量(M.W.) | 382.88 |
储存条件 | 2-8°C储存 |
Reaxys-RN | 3917363 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg |
信号词 | Warning |
危害声明 | H315-H319-H335 |
警示性声明 | P261-P305 + P351 + P338 |
个人防护设备 | dust mask type N95 (US), Eyeshields, Gloves |
RTECS | DO1925000 |
WGK德国 | 2 |
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