存贮条件 | 储存温度2-8°C |
密度 | 1.5600 |
产品介绍 | Staurosporine is a potent PKC inhibitor for PKCα, PKCγ and PKCη with IC50 of 2 nM, 5 nM and 4 nM, less potent to PKCδ (20 nM), PKCε (73 nM) and little active to PKCζ (1086 nM). Phase 3. |
生化机理 | Staurosporine (Stsp) is potent inhibitor of protein kinase C (PKC) from rat brain, exhibiting an IC50 value of 2.7 nM. It inhibits rat recombinant PKC-α approximately 100- and 1,000-fold better than PKC-δ and PKC-ζ, respectively.2 However, Stsp is non-selective in that it also inhibits the activity of a variety of other protein kinases, not only PKC isoforms. The biological effects of Stsp include cytotoxicity, relaxation of smooth muscle, and regulation of eNOS gene expression. |
别名 | Antibiotic AM-2282;Antibiotic AM-2282 |
星形孢菌素
Staurosporine (订货以英文为准)
编号:S102392
CAS号:62996-74-1
分子式:C28H26N4O3
分子量:466.53
产品名称 | Staurosporine |
中文名称 | 星形孢菌素 |
CAS号 | 62996-74-1 |
分子式(M.F.) | C28H26N4O3 |
分子量(M.W.) | 466.53 |
储存条件 | 2-8°C储存 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs06.jpg,https://www.aladdin-e.com/images/ghs/ghs08.jpg |
信号词 | Danger |
危害声明 | H301,H315,H319,H335,H340,H350 |
警示性声明 | P201,P261,P301+P310,P305+P351+P338,P308+P313 |
WGK德国 | 3 |
风险声明 (欧洲) | 22,36/37/38 |
安全声明(欧洲) | 26 |
危害码(欧洲) | Xn |
UN代码 | 2811 |
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