星形孢菌素

Staurosporine (订货以英文为准)

编号:S102392
CAS号:62996-74-1
分子式:C28H26N4O3
分子量:466.53
货号 品牌 包装 目录价 您的价格 库存 数量 购买
S102392-1mg 阿拉丁 1mg ¥360.90
S102392-5mg 阿拉丁 5mg ¥1174.90
产品名称 Staurosporine
中文名称 星形孢菌素
CAS号 62996-74-1
分子式(M.F.) C28H26N4O3
分子量(M.W.) 466.53
储存条件 2-8°C储存
存贮条件储存温度2-8°C
密度1.5600
产品介绍Staurosporine is a potent PKC inhibitor for PKCα, PKCγ and PKCη with IC50 of 2 nM, 5 nM and 4 nM, less potent to PKCδ (20 nM), PKCε (73 nM) and little active to PKCζ (1086 nM). Phase 3.
生化机理Staurosporine (Stsp) is potent inhibitor of protein kinase C (PKC) from rat brain, exhibiting an IC50 value of 2.7 nM. It inhibits rat recombinant PKC-α approximately 100- and 1,000-fold better than PKC-δ and PKC-ζ, respectively.2 However, Stsp is non-selective in that it also inhibits the activity of a variety of other protein kinases, not only PKC isoforms. The biological effects of Stsp include cytotoxicity, relaxation of smooth muscle, and regulation of eNOS gene expression.
别名Antibiotic AM-2282;Antibiotic AM-2282
标识符号https://www.aladdin-e.com/images/ghs/ghs06.jpg,https://www.aladdin-e.com/images/ghs/ghs08.jpg
信号词Danger
危害声明H301,H315,H319,H335,H340,H350
警示性声明P201,P261,P301+P310,P305+P351+P338,P308+P313
WGK德国3
风险声明 (欧洲)22,36/37/38
安全声明(欧洲)26
危害码(欧洲)Xn
UN代码2811
搜索质检报告(COA)
搜索MSDS
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