| 溶解性 | DMSO 185 mg/mL Water <1 mg/mL Ethanol <1 mg/mL |
| 存贮条件 | 储存温度2-8℃ |
| 产品介绍 | Lapatinib (GW-572016) Ditosylate是一种有效的EGFR和ErbB2抑制剂，IC50分别为10.8和9.2 nM。 |
| 备注 | Lapatinib Ditosylate (GW572016, GW2016) is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively. |
| 生化机理 | Lapatinib ditosylate is a selective and effective inhibitor of ErbB-2 and EGFR dual tyrosine kinases. ErbB-2 and EGFR dual tyrosine kinases are growth promoting factors that are over expressed in some breast cancer cell lines. Research studies have reported that Lapatinib Ditosylate can inhibit breast cancer cell proliferation. |
| 别名 | 二对甲苯磺酸拉帕替尼;N-[3-氯-4-[(3-氟苯基)甲氧基]苯基]-6-[5-[(2-甲磺酰乙基氨基)甲基]-2-呋喃基]喹唑啉-4-胺 二对甲苯磺酸盐;Tykerb ditosylate; GW 572016 ditosylate; GW-572016 ditosylate; Lapatinib ditosylate; |
二对甲苯磺酸拉帕替尼(GW-572016)
Lapatinib Ditosylate(GW-572016) （订货以英文为准）
编号：L129338
CAS号：388082-77-7
分子式：C29H26CLFN4O4S.2C7H8O3S
分子量：925.46
| 产品名称 | Lapatinib Ditosylate(GW-572016) |
| 中文名称 | 二对甲苯磺酸拉帕替尼(GW-572016) |
| CAS号 | 388082-77-7 |
| 分子式（M.F.） | C29H26CLFN4O4S.2C7H8O3S |
| 分子量（M.W.） | 925.46 |
| 储存条件 | 2-8°C储存 |
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