| 溶解性 | DMSO 65 mg/mL Water <1 mg/mL Ethanol <1 mg/mL |
| 存贮条件 | 储存温度-20°C |
| 备注 | Scriptaid is an inhibitor of HDAC. It shows a greater effect on acetylated H4 than H3. |
| 生化机理 | A novel HDAC inhibitor, Scriptaid, has been found to have robust activity and lower toxicity compared to trichostatin A (TSA). Although Scriptaid induced activation of both p38MAPK and JNK, it was the inhibition of JNK that attenuated Scriptaid-induced apoptosis significantly. Scriptaid also increased the expression of (i) p21 and p27 involved in cell-cycle regulation and (ii) γH2AX associated with DNA damage response in a JNK-dependent manner. |
| 别名 | Scriptide, GCK 1026;1H-Benz[de]isoquinoline-2(3H)-hexanamide, N-hydroxy-1,3-dioxo-;Scriptide, GCK 1026;1H-Benz[de]isoquinoline-2(3H)-hexanamide, N-hydroxy-1,3-dioxo- |
Scriptaid,HDAC抑制剂
Scriptaid （订货以英文为准）
编号：S125104
CAS号：287383-59-9
分子式：C18H18N2O4
分子量：326.35
| 产品名称 | Scriptaid |
| 中文名称 | Scriptaid,HDAC抑制剂 |
| CAS号 | 287383-59-9 |
| 分子式（M.F.） | C18H18N2O4 |
| 分子量（M.W.） | 326.35 |
| 储存条件 | 避光;-20°C储存 |
| RTECS | VB1983750 |
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