| 敏感性 | 对光线敏感 |
| 溶解性 | DMSO: >10 mg/mL |
| 存贮条件 | 储存温度-20°C |
| 生化机理 | Combretastatin A4 is a vascular disrupting agent (VDA) that targets tumor vasculature to inhibit angiogenesis. It inhibits tubulin polymerization at the colchicine-binding site of beta-tubulin. It has antitumor activity by inhibiting AKT function in human gastric cells. The inhibited AKT activation causes decreased cell proliferation, cell cycle arrest, and reduced in vitro migration/invasiveness and in vivo metastatic ability. Combretastatin A4 is a natural stilbenoid phenol. |
| 别名 | (Z)-2-甲氧基-5-(3,4,5-三甲氧基苯乙烯基)苯酚;3'-羟基-3,4,4',5-四甲氧基-顺-芪;(Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol;3'-Hydroxy-3,4,4',5-tetramethoxy-cis-stilbene;1-(3,4,5-Trimethoxyphenyl)-2-(3′-hydroxy-4′-methoxyphenyl) ethane 3,4,5-trimethoxy-3′-hydroxy-4′-methoxystilbene;2-Methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol,;CA4 |
考布他汀A4
Combretastatin A4 （订货以英文为准）
编号：C153431
CAS号：117048-59-6
分子式：C18H20O5
分子量：316.35
| 产品名称 | Combretastatin A4 |
| 中文名称 | 考布他汀A4 |
| CAS号 | 117048-59-6 |
| MDL编码 | MFCD03453309 |
| 分子式（M.F.） | C18H20O5 |
| 分子量（M.W.） | 316.35 |
| 储存条件 | -20°C储存 |
| Reaxys-RN | 1905834 |
| 个人防护设备 | Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter |
| RTECS | DA3200000 |
| WGK德国 | 3 |
| UN代码 | 1325 |
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