溶解性 | DMSO ≥83mg/mL Water <1.2mg/mL Ethanol ≥2.6mg/mL |
存贮条件 | 储存温度-20°C |
应用 | A potent inhibitor of MEK1 and MEK2. |
产品介绍 | Pimasertib (AS-703026) is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2 with IC50 of 5 nM-2 μM in MM cell lines. |
备注 | AS-703026 is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2 with IC50 of 5 nM-2 μM in MM cell lines. Phase 1/2. |
生化机理 | AS703026 is a highly selective and potent noncompetitive inhibitor of MEK1 and MEK2 (IC50 = 5-11 nM). |
别名 | MSC1936369B;AS703026;N-[(2S)-2,3-二羟基丙基]-3-[(2-氟-4-碘苯基)氨基]-4-吡啶甲酰胺;MSC1936369B;AS-703026;AS 703026;N-[(2S)-2,3-Dihydroxypropyl]-3-[(2-fluoro-4-iodophenyl)amino]-4-pyridinecarboxamide |
N-[(2S)-2,3-二羟基丙基]-3-[(2-氟-4-碘苯基)氨基]-4-吡啶甲酰胺
Pimasertib (AS-703026) (订货以英文为准)
编号:A125227
CAS号:1236699-92-5
分子式:C15H15FIN3O3
分子量:431.20
产品名称 | Pimasertib (AS-703026) |
中文名称 | N-[(2S)-2,3-二羟基丙基]-3-[(2-氟-4-碘苯基)氨基]-4-吡啶甲酰胺 |
CAS号 | 1236699-92-5 |
分子式(M.F.) | C15H15FIN3O3 |
分子量(M.W.) | 431.20 |
储存条件 | -20°C储存 |
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