N-[(2S)-2,3-二羟基丙基]-3-[(2-氟-4-碘苯基)氨基]-4-吡啶甲酰胺

Pimasertib (AS-703026) (订货以英文为准)

编号:A125227
CAS号:1236699-92-5
分子式:C15H15FIN3O3
分子量:431.20
货号 品牌 包装 目录价 您的价格 库存 数量 购买
A125227-50mg 阿拉丁 50mg ¥1639.90
A125227-5mg 阿拉丁 5mg ¥299.90
A125227-10mg 阿拉丁 10mg ¥471.90
产品名称 Pimasertib (AS-703026)
中文名称 N-[(2S)-2,3-二羟基丙基]-3-[(2-氟-4-碘苯基)氨基]-4-吡啶甲酰胺
CAS号 1236699-92-5
分子式(M.F.) C15H15FIN3O3
分子量(M.W.) 431.20
储存条件 -20°C储存
溶解性DMSO ≥83mg/mL Water <1.2mg/mL Ethanol ≥2.6mg/mL
存贮条件储存温度-20°C
应用A potent inhibitor of MEK1 and MEK2.
产品介绍Pimasertib (AS-703026) is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2 with IC50 of 5 nM-2 μM in MM cell lines.
备注AS-703026 is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2 with IC50 of 5 nM-2 μM in MM cell lines. Phase 1/2.
生化机理AS703026 is a highly selective and potent noncompetitive inhibitor of MEK1 and MEK2 (IC50 = 5-11 nM).
别名MSC1936369B;AS703026;N-[(2S)-2,3-二羟基丙基]-3-[(2-氟-4-碘苯基)氨基]-4-吡啶甲酰胺;MSC1936369B;AS-703026;AS 703026;N-[(2S)-2,3-Dihydroxypropyl]-3-[(2-fluoro-4-iodophenyl)amino]-4-pyridinecarboxamide
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