熔点 | 255°C-270°C |
敏感性 | 对光线和湿度敏感,易吸潮 |
溶解性 | Readily soluble in chloroform, acetonitrile, acetone, dioxane, tetrahydrofuran, pyridine; soluble in ethanol, methanol, 1-propanol, ethyl acetate and n-butanol; insoluble in water, 2-propanol |
存贮条件 | 储存温度-20℃ |
应用 | K252a is a highly potent cell permeable inhibitor of CaM kinase and phosphorylase kinase . At high concentrations it also inhibitors of serine/threonine protein kinasesK252a inhibits tyrosine phosphorylation of Trk A induced by NGFK252a is reported to promote myogenic differentiation in C2 mouse myoblasts |
产品介绍 | K252a: Cell permeable protein kinase inhibitor |
别名 | ;Antibiotic K-252a;Antibiotic SF 2370;Protein Kinase Inhibitor;(8R*, 9S*, 11S*)-(-)-9-hydroxy-9-methoxycarbonyl-8-methyl-2,3,9,10-tetrahydro-8,11-epoxy-1H, 8H, 11H-2, 7b, 11a-triazadibenzo(a,g)cycloocta(cde)trinden-1-one |
K-252a,蛋白质和CAM激酶抑制剂
K-252a (订货以英文为准)
编号:K139531
CAS号:99533-80-9
分子式:C27H21N3O5
分子量:467.47
产品名称 | K-252a |
中文名称 | K-252a,蛋白质和CAM激酶抑制剂 |
CAS号 | 99533-80-9 |
MDL编码 | MFCD00161522 |
分子式(M.F.) | C27H21N3O5 |
分子量(M.W.) | 467.47 |
储存条件 | 避光;-20°C储存;充氩 |
个人防护设备 | Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter |
RTECS | LX8930000 |
WGK德国 | 3 |
安全声明(欧洲) | 22,24/25 |
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