| 敏感性 | 对热敏感 |
| 溶解性 | solubility in DMSO:20 mg/mL, clear |
| 存贮条件 | 储存温度-20°C |
| 生化机理 | Description:IC50 Value: N/ANoopept (GVS-111) is a medication promoted and prescribed in Russia and neighbouring countries as a nootropic.in vitro: Nooglutil exhibits pharmacologically significant competition with a selective agonist of AMPA receptors ([G-3H]Ro 48-8587) for the receptor binding sites (with IC50 = 6.4 +/- 0.2 microM), while the competition of noopept for these receptor binding sites was lower by an order of magnitude (IC50 = 80 +/- 5.6 microM) [1]. GVS-111 significantly increased neuronal survival after H(2)O(2)-treatment displaying a dose-dependent neuroprotective activity from 10 nM to 100 microM, and an IC(50) value of 1.21+/-0.07 microM. GVS-111 inhibited the accumulation of intracellular free radicals and lipid peroxidation damage in neurons treated with H(2)O(2) or FeSO(4), suggesting an antioxidant mechanism of action [2].in vivo: N-Phenylacetyl-L-prolylglycine ethyl ester (GVS-111) administered intravenously at a dose of 0 |
| 别名 | N-(1-(苯基乙酰基)-L-脯氨酰)甘氨酸乙酯;1-(2-Phenylacetyl)-L-prolyl-glycine ethyl ester；GVS 111；N-Phenylacetyl-L-prolylglycine ethyl ester；SGS 111；Ethyl N-[1-(Phenylacetyl)-L-prolyl]glycinate |
Noopept,促智和神经保护药
Noopept （订货以英文为准）
编号：N126590
CAS号：157115-85-0
分子式：C17H22N2O4
分子量：318.37
| 产品名称 | Noopept |
| 中文名称 | Noopept,促智和神经保护药 |
| CAS号 | 157115-85-0 |
| 分子式（M.F.） | C17H22N2O4 |
| 分子量（M.W.） | 318.37 |
| 储存条件 | -20°C储存 |
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