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Noopept,促智和神经保护药

Noopept （订货以英文为准）

编号：N126590
CAS号：157115-85-0
分子式：C17H22N2O4
分子量：318.37
货号 品牌 包装 目录价 您的价格 库存 数量 购买
N126590-5g 阿拉丁 5g ¥108.90
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N126590-25g 阿拉丁 25g ¥307.90
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N126590-1g 阿拉丁 1g ¥46.90
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N126590-200mg 阿拉丁 200mg ¥29.90
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N126590-100g 阿拉丁 100g ¥1102.90
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产品名称 Noopept
中文名称 Noopept,促智和神经保护药
CAS号 157115-85-0
MDL编码 MFCD00941121
分子式（M.F.） C17H22N2O4
分子量（M.W.） 318.37
储存条件 -20°C储存
敏感性对热敏感
溶解性solubility in DMSO:20 mg/mL, clear
存贮条件储存温度-20°C
生化机理Description:IC50 Value: N/ANoopept (GVS-111) is a medication promoted and prescribed in Russia and neighbouring countries as a nootropic.in vitro: Nooglutil exhibits pharmacologically significant competition with a selective agonist of AMPA receptors ([G-3H]Ro 48-8587) for the receptor binding sites (with IC50 = 6.4 +/- 0.2 microM), while the competition of noopept for these receptor binding sites was lower by an order of magnitude (IC50 = 80 +/- 5.6 microM) [1]. GVS-111 significantly increased neuronal survival after H(2)O(2)-treatment displaying a dose-dependent neuroprotective activity from 10 nM to 100 microM, and an IC(50) value of 1.21+/-0.07 microM. GVS-111 inhibited the accumulation of intracellular free radicals and lipid peroxidation damage in neurons treated with H(2)O(2) or FeSO(4), suggesting an antioxidant mechanism of action [2].in vivo: N-Phenylacetyl-L-prolylglycine ethyl ester (GVS-111) administered intravenously at a dose of 0
别名N-(1-(苯基乙酰基)-L-脯氨酰)甘氨酸乙酯;1-(2-Phenylacetyl)-L-prolyl-glycine ethyl ester；GVS 111；N-Phenylacetyl-L-prolylglycine ethyl ester；SGS 111；Ethyl N-[1-(Phenylacetyl)-L-prolyl]glycinate
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