唑替丁

Zaltidine (订货以英文为准)

编号:Z127855
CAS号:85604-00-8
分子式:C8H10N6S
分子量:222.27
货号 品牌 包装 目录价 您的价格 库存 数量 购买
Z127855-5mg 阿拉丁 5mg ¥1956.90
Z127855-10mg 阿拉丁 10mg ¥3129.90
Z127855-50mg 阿拉丁 50mg ¥8617.90
产品名称 Zaltidine
中文名称 唑替丁
CAS号 85604-00-8
分子式(M.F.) C8H10N6S
分子量(M.W.) 222.27
储存条件 -20°C储存
溶解性DMSO
存贮条件储存温度-20°C
生化机理Description:IC50 Value: N/AZaltidine is a H2-receptor antagonist, which has the antisecretory action.in vitro: N/Ain vivo: In eight healthy male volunteers single oral doses of 5 mg, 25 mg and 100 mg produced dose-related inhibition of basal and pentagastrin-stimulated acid output (M.A.O.) with an estimated ID50 of 40 mg for the latter. In eight subjects with duodenal ulceration single 100 mg and 200 mg doses produced 85% and 97% inhibition of M.A.O. at peak (3 h post-dose) and 20% and 23% inhibition at 24 h, respectively; inhibition of basal acid output was 97% at 3 h and 50% at 24 h with both doses [1]. One hundred and thirty-five patients were randomly allocated to 4 weeks' treatment with either 150 mg zaltidine once daily or placebo. Fifty-nine were treated for a full 4 weeks with zaltidine before the trial was stopped. Healing rates after 4 weeks of zaltidine and placebo were 86% and 19%, respectively (p less than 0.001) [2].Clinical trial: N/A
标识符号https://www.aladdin-e.com/images/ghs/ghs07.jpg,https://www.aladdin-e.com/images/ghs/ghs08.jpg
信号词Warning
危害声明H302-H351
警示性声明P281
个人防护设备Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RTECSDP3750000
WGK德国3
搜索质检报告(COA)
搜索MSDS
相关产品