西替利嗪

Cetirizine (订货以英文为准)

编号:C127824
CAS号:83881-51-0
分子式:C21H25CLN2O3
分子量:388.89
货号 品牌 包装 目录价 您的价格 库存 数量 购买
C127824-100mg 阿拉丁 100mg ¥361.90
C127824-1g 阿拉丁 1g ¥2299.90
C127824-500mg 阿拉丁 500mg ¥1259.90
产品名称 Cetirizine
中文名称 西替利嗪
CAS号 83881-51-0
分子式(M.F.) C21H25CLN2O3
分子量(M.W.) 388.89
储存条件 -20°C储存
溶解性DMSO
存贮条件储存温度-20°C
生化机理Cetirizine, a second-generation antihistamine, is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist used in the treatment of allergies, hay fever, angioedema, and urticaria. Cetirizine crosses the blood-brain barrier only slightly, reducing the sedative side-effect common with older antihistamines. It has also been shown to inhibit eosinophil chemotaxis and LTB4 release. At a dosage of 20 mg, Boone et al. found that it inhibited the expression of VCAM-1 in patients with atopic dermatitis. The levorotary enantiomer of cetirizine, known as levocetirizine, is the more active form. From Wikipedia.
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