熔点 | 260 °C |
溶解性 | Soluble in DMSO (>10 mg/ml), water (25 mg/ml) Note: Phosphate-containing buffers may cause precipitation, and ethanol (<1 mg/mL) at 25 °C. |
存贮条件 | 储存温度 2-8°C |
应用 | A highly effective tryptase inhibitor. |
产品介绍 | Nafamostat Mesylate是一种抗凝血剂。 |
备注 | Nafamostat Mesylate is an anticoagulant. |
生化机理 | Nafamostat mesylate is a highly effective tryptase (Ki=95.3 pM) inhibitor. The compound has the ability to promote synthesis of interferon-γ, tumor necrosis factor-α, IL-12, and IL-18. Additionally, Nafamostat mesylate can induce production of intercellular adhesion molecules-1, B7.1, B7.2, CD40 and CD40 ligand in human blood mononuclear cells. Nafamostat mesylate is an anticoagulant and has been shown to decrease levels of plasma myeloperoxidase, and has also been used in ERCP pancreatitis studies. Nafamostat mesylate is an inhibitor of Factor X, Factor XII, granzyme A and KLK. |
别名 | 萘莫司他甲磺酸盐;甲磺酸萘莫司他; FUT-175;6-脒基-2-萘基 4-胍基苯甲酸酯甲基磺酸盐;Coahibitor; FUT-175; Futhan;6-Amidino-2-naphthyl 4-Guanidinobenzoate Bis(methanesulfonate);4-Guanidinobenzoic Acid 6-Amidino-2-naphthyl Ester Bis(methanesulfonate) |
甲磺酸萘莫司他
Nafamostat Mesylate (订货以英文为准)
编号:N129262
CAS号:82956-11-4
分子式:C19H17N5O2.2CH4O3S
分子量:539.58
产品名称 | Nafamostat Mesylate |
中文名称 | 甲磺酸萘莫司他 |
CAS号 | 82956-11-4 |
分子式(M.F.) | C19H17N5O2.2CH4O3S |
分子量(M.W.) | 539.58 |
储存条件 | 2-8°C储存;避光 |
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