甲磺酸萘莫司他

Nafamostat Mesylate (订货以英文为准)

编号:N129262
CAS号:82956-11-4
分子式:C19H17N5O2.2CH4O3S
分子量:539.58
货号 品牌 包装 目录价 您的价格 库存 数量 购买
N129262-50mg 阿拉丁 50mg ¥98.90
N129262-10mg 阿拉丁 10mg ¥32.90
N129262-250mg 阿拉丁 250mg ¥329.90
N129262-1g 阿拉丁 1g ¥1029.90
N129262-5g 阿拉丁 5g ¥3501.90
产品名称 Nafamostat Mesylate
中文名称 甲磺酸萘莫司他
CAS号 82956-11-4
分子式(M.F.) C19H17N5O2.2CH4O3S
分子量(M.W.) 539.58
储存条件 2-8°C储存;避光
熔点260 °C
溶解性Soluble in DMSO (>10 mg/ml), water (25 mg/ml) Note: Phosphate-containing buffers may cause precipitation, and ethanol (<1 mg/mL) at 25 °C.
存贮条件储存温度 2-8°C
应用A highly effective tryptase inhibitor.
产品介绍Nafamostat Mesylate是一种抗凝血剂。
备注Nafamostat Mesylate is an anticoagulant.
生化机理Nafamostat mesylate is a highly effective tryptase (Ki=95.3 pM) inhibitor. The compound has the ability to promote synthesis of interferon-γ, tumor necrosis factor-α, IL-12, and IL-18. Additionally, Nafamostat mesylate can induce production of intercellular adhesion molecules-1, B7.1, B7.2, CD40 and CD40 ligand in human blood mononuclear cells. Nafamostat mesylate is an anticoagulant and has been shown to decrease levels of plasma myeloperoxidase, and has also been used in ERCP pancreatitis studies. Nafamostat mesylate is an inhibitor of Factor X, Factor XII, granzyme A and KLK.
别名萘莫司他甲磺酸盐;甲磺酸萘莫司他; FUT-175;6-脒基-2-萘基 4-胍基苯甲酸酯甲基磺酸盐;Coahibitor; FUT-175; Futhan;6-Amidino-2-naphthyl 4-Guanidinobenzoate Bis(methanesulfonate);4-Guanidinobenzoic Acid 6-Amidino-2-naphthyl Ester Bis(methanesulfonate)
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