维达列汀 (LAF-237)

Vildagliptin (LAF-237) (订货以英文为准)

编号:V125454
CAS号:274901-16-5
分子式:C17H25N3O2
分子量:303.40
货号 品牌 包装 目录价 您的价格 库存 数量 购买
V125454-10mg 阿拉丁 10mg ¥30.90
V125454-5g 阿拉丁 5g ¥205.90
V125454-25g 阿拉丁 25g ¥778.90
V125454-1g 阿拉丁 1g ¥66.90
V125454-100g 阿拉丁 100g ¥2351.90
V125454-50mg 阿拉丁 50mg ¥51.90
V125454-500g 阿拉丁 500g ¥8614.90
V125454-10g 阿拉丁 10g ¥373.90
产品名称 Vildagliptin (LAF-237)
中文名称 维达列汀 (LAF-237)
CAS号 274901-16-5
MDL编码 MFCD08275142
分子式(M.F.) C17H25N3O2
分子量(M.W.) 303.40
储存条件 -20°C储存;充氩
溶解性Soluble in DMSO and Water
存贮条件储存温度-20°C
应用A CD26 inhibitor associated with immune response inhibition
产品介绍Vildagliptin is a dipeptidyl peptidase-4 (CD26) inhibitor. CD26 activates serine proteases in immune/inflammatory cells. Vildagliptin also inhibits dipeptidyl-peptidase 8 (DPRP1) and dipeptidyl-peptidase 9 (DPRP2), which have been correlated to T cell activation and immune function, as well as diabetes and cancer regulation.
备注Vildagliptin (LAF-237) inhibits DPP?4 with IC50 of 2.3 nM.
生化机理Vildagliptin (LAF-237)抑制DPP?4,IC50为2.3 nM。
别名维达列汀;维他列汀;(-)-(2S)-1-[[(3-羟基三环[3.3.1.1(3,7)]癸烷-1-基)氨基]乙酰基]吡咯烷-2-甲腈;LAF237;Galvus;NVP-LAF 237;Zomelis;1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-, (2S)-2-Pyrrolidinecarbonitrile
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