溶解性 | Soluble in DMSO and Water |
存贮条件 | 储存温度-20°C |
应用 | A CD26 inhibitor associated with immune response inhibition |
产品介绍 | Vildagliptin is a dipeptidyl peptidase-4 (CD26) inhibitor. CD26 activates serine proteases in immune/inflammatory cells. Vildagliptin also inhibits dipeptidyl-peptidase 8 (DPRP1) and dipeptidyl-peptidase 9 (DPRP2), which have been correlated to T cell activation and immune function, as well as diabetes and cancer regulation. |
备注 | Vildagliptin (LAF-237) inhibits DPP?4 with IC50 of 2.3 nM. |
生化机理 | Vildagliptin (LAF-237)抑制DPP?4,IC50为2.3 nM。 |
别名 | 维达列汀;维他列汀;(-)-(2S)-1-[[(3-羟基三环[3.3.1.1(3,7)]癸烷-1-基)氨基]乙酰基]吡咯烷-2-甲腈;LAF237;Galvus;NVP-LAF 237;Zomelis;1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-, (2S)-2-Pyrrolidinecarbonitrile |
维达列汀 (LAF-237)
Vildagliptin (LAF-237) (订货以英文为准)
编号:V125454
CAS号:274901-16-5
分子式:C17H25N3O2
分子量:303.40
产品名称 | Vildagliptin (LAF-237) |
中文名称 | 维达列汀 (LAF-237) |
CAS号 | 274901-16-5 |
MDL编码 | MFCD08275142 |
分子式(M.F.) | C17H25N3O2 |
分子量(M.W.) | 303.40 |
储存条件 | -20°C储存;充氩 |
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