| 熔点 | 210°C |
| 旋光率 | 114 to 122 deg(C=1, H2O) |
| 敏感性 | 对空气、光线、热敏感 |
| 溶解性 | Soluble in water at 50mg/ml |
| 存贮条件 | 贮存温度2-8°C;充氩保存 |
| 应用 | (+)-cis-Diltiazem hydrochloride has been used:· to study its effects on diffusion and release in monolithic dispersion matrix· to study its neuroprotective effects in retinitis pigmentosa (RP) models· as an antagonist against the Cav1.2 L-type calcium channels (LTCCs) |
| 产品介绍 | Diltiazem HCl 是一种Benzothiazepine衍生物，具有舒张血管的作用，由于其抑制钙离子在膜的功能。Diltiazem hydrochloride is used to treat cardiovascular diseases, such as angina and hypertension. It acts as an inhibitor to cytochrome P450 3A (CYP3A). Diltiazem might be associated with maculopapular rashes, urticaria and pruritus. |
| 生化机理 | 封闭缓慢或L-型Ca2+通道；调节来自中性粒细胞内存储的Ca2+的释放；刺激1,4-二氢吡啶结合至Ca2+通道；冠状动脉舒张剂。 |
| 别名 | 盐酸地尔硫卓;(+)-顺-地尔硫卓盐酸盐;硫氮卓酮;顺-(+)-5-[(2-二甲氨基)乙基]-2-(4-甲氧基苯基)-3-乙酰氧基-2,3-二氢-1,5-苯并硫氮杂卓-4(5H)酮盐酸盐;Diltiazem hydrochloride;(+)-cis-Diltiazem Hydrochloride;(2S,3S)-(+)-3-Acetoxy-2,3-dihydro-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride |
盐酸地尔硫卓
Diltiazem HCl （订货以英文为准）
编号：C154045
CAS号：33286-22-5
分子式：C22H26N2O4S.HCL
分子量：450.98
| 产品名称 | Diltiazem HCl |
| 中文名称 | 盐酸地尔硫卓 |
| CAS号 | 33286-22-5 |
| 分子式（M.F.） | C22H26N2O4S.HCL |
| 分子量（M.W.） | 450.98 |
| 储存条件 | 2-8°C储存;充氩 |
| 标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg |
| 信号词 | Warning |
| 危害声明 | H302,H315,H319,H335 |
| 警示性声明 | P261,P305+P351+P338 |
| 个人防护设备 | dust mask type N95 (US),Eyeshields,Gloves |
| RTECS | LV0944000 |
| WGK德国 | 3 |
| 风险声明 (欧洲) | R22;R36/37/38; |
| 安全声明（欧洲） | S26; |
| 危害码（欧洲） | Xn |
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