概述
Fusion protein corresponding to a region derived from 103-287 amino acids of human ARHGEF9
技术规格
| Full name: | Cdc42 guanine nucleotide exchange factor (GEF) |
| Synonyms: | PEM2; EIEE8; PEM-2; HPEM-2; COLLYBISTIN |
| Swissprot: | O43307 |
| Gene Accession: | BC117406 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Background: | The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene. |
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