概述
Fusion protein corresponding to N terminal 304 amino acids of human APP
技术规格
| Full name: | amyloid beta (A4) precursor protein |
| Synonyms: | AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma |
| Swissprot: | P05067 |
| Gene Accession: | BC004369 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Background: | This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. |
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