概述
Fusion protein corresponding to C terminal 250 amino acids of human ARSA
技术规格
Full name: | arylsulfatase A |
Synonyms: | MLD |
Swissprot: | P15289 |
Gene Accession: | BC014210 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Background: | The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene. |