概述
Fusion protein corresponding to a region derived from 208-407 amino acids of human ADRM1
技术规格
| Full name: | adhesion regulating molecule 1 |
| Synonyms: | ARM1; ARM-1; GP110 |
| Swissprot: | Q16186 |
| Gene Accession: | BC017245 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Background: | This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. |
党沛 
