概述
Fusion protein corresponding to a region derived from 87-203 amino acids of human ARL6IP1
技术规格
Full name: | ADP-ribosylation factor-like 6 interacting protein 1 |
Synonyms: | AIP1; ARMER; SPG61; ARL6IP |
Swissprot: | Q15041 |
Gene Accession: | BC010281 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Background: | This gene belongs to the ARL6ip family and encodes a transmembrane protein that is predominantly localized to intracytoplasmic membranes. It is highly expressed in early myeloid progenitor cells and thought to be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Mutations in this gene are associated with spastic paraplegia 61 (SPG61). Alternatively spliced transcript variants have been found for this gene. |