概述
Fusion protein corresponding to a region derived from 1-73 amino acids of human ABRAXAS1
技术规格
| Full name: | abraxas 1, BRCA1 A complex subunit |
| Synonyms: | ABRA1; CCDC98; FAM175A |
| Swissprot: | Q6UWZ7 |
| Gene Accession: | BC016905 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Background: | This gene encodes a protein that binds to the C-terminal repeats of breast cancer 1 (BRCA1) through a phospho-SXXF motif. The encoded protein recruits ubiquitin interaction motif containing 1 protein to BRCA1 protein and is required for DNA damage resistance, DNA repair, and cell cycle checkpoint control. Pseudogenes of this gene are found on chromosomes 3 and 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] |
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