概述
Fusion protein corresponding to a region derived from 590-824 amino acids of human ABCB6
技术规格
| Full name: | ATP-binding cassette, sub-family B (MDR/TAP), member 6 |
| Synonyms: | ABC; LAN; PRP; umat; ABC14; MTABC3; MCOPCB7 |
| Swissprot: | Q9NP58 |
| Gene Accession: | BC000559 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Background: | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function. |
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