概述
Fusion protein corresponding to C terminal 250 amino acids of human ACADS
技术规格
| Full name: | Acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| Synonyms: | SCAD; ACAD3 |
| Swissprot: | P16219 |
| Gene Accession: | BC025963 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Background: | This gene encodes a a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with Short Chain Acyl-CoA Dehydrogenase Deficiency. It is an autosomal recessive disorder resulting in acute acidosis and muscle weakness in infants, and a form of lipid-storage myopathy in adults. |
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