概述
Fusion protein corresponding to a region derived from 401-651 amino acids of human ABLIM1
技术规格
Full name: | Actin binding LIM protein 1 |
Synonyms: | ABLIM; LIMAB1; LIMATIN; abLIM-1 |
Swissprot: | O14639 |
Gene Accession: | BC002448 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Background: | This gene encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions. The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified. |