甲氧氯普胺

Metoclopramide (订货以英文为准)

编号:M124438
CAS号:364-62-5
分子式:C14H22CLN3O2
分子量:299.80
货号 品牌 包装 目录价 您的价格 库存 数量 购买
M124438-5g 阿拉丁 5g ¥50.90
M124438-25g 阿拉丁 25g ¥145.90
M124438-100g 阿拉丁 100g ¥439.90
产品名称 Metoclopramide
中文名称 甲氧氯普胺
CAS号 364-62-5
MDL编码 MFCD00211338
分子式(M.F.) C14H22CLN3O2
分子量(M.W.) 299.80
储存条件 2-8°C储存
熔点149°C
溶解性Soluble in water (miscible), and ethanol.
存贮条件储存温度2-8℃
生化机理Metoclopramide is a dopamine receptor antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In various countries, metoclopramide is the antiemetic drug of choice in pregnant women. Findings provide reassurance regarding the safety of metoclopramide for the fetus when the drug is given to women to relieve nausea and vomiting during pregnancy. Evidence also supports its use for gastroparesis (poor stomach emptying) and gastroesophageal reflux disease. It appears to bind to dopamine D2 receptors where it is a receptor antagonist, and is also a mixed 5-HT3 receptor antagonist/ 5-HT4 receptor agonist.
别名4-氨基-5-氯-N-[2-(二乙氨基)乙基]-2-甲氧基苯甲酰胺4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide Methoxychloroprocainamide
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