熔点 | 166°C |
溶解性 | Soluble in DMSO, methanol, water (83 mg/ml) at 23 °C, chloroform, ethanol, and propylene glycol (30 mg/mL) at 23 °C. |
存贮条件 | 储存温度-20°C |
应用 | A HIV reverse transcriptase (HIV-1 RT) inhibitor |
产品介绍 | Stavudine (d4T)是一种核苷类似物逆转录酶抑制剂(NARTI),有效作用于HIV。 |
备注 | Stavudine is a nucleoside analog reverse transcriptase inhibitor (NARTI) active against HIV. |
生化机理 | 3'-Deoxy-2',3'-didehydrothymidine is a HIV-1 RT (HIV reverse transcriptase) inhibitor that causes a consistent and rapid shortening of telomeres in Tetrahymera. 3'-Deoxy-2',3'-didehydrothymidine has been shown to decrease the proliferative activity of Jurkat and L1210 cell lines as well as human peripheral blood mononuclear cells at 250 μM concentration. |
别名 | 司他呋啶;2',3'-二脱氢-3'-脱氧胸苷;3'-脱氧-2',3'-双脱氢胸甙;3'-脱氧-2',3'-双脱氢胸苷;司他夫定;Sanilvudine;d4T;2',3'-Anhydrothymidine;1-(2,3-Dideoxy-β-D-glycero-2-pentenofuranosyl)thymine;1-[(2R,5S)-5-(Hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-(1H,3H)-dione;2',3'-Didehydro-3'-deoxythymidine;Zerit |
2',3'-二脱氢-3'-脱氧胸苷
Stavudine (d4T) (订货以英文为准)
编号:S129783
CAS号:3056-17-5
分子式:C10H14N2O4
分子量:226.23
产品名称 | Stavudine (d4T) |
中文名称 | 2',3'-二脱氢-3'-脱氧胸苷 |
CAS号 | 3056-17-5 |
分子式(M.F.) | C10H14N2O4 |
分子量(M.W.) | 226.23 |
储存条件 | -20°C储存 |
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