熔点 | 148°C |
旋光率 | 38 ° (C=1, H2O) |
敏感性 | 对热敏感 |
溶解性 | Soluble in water, alcohol, isopropyl alcohol, methanol, aqueous buffers, acetone, dimethyl sulfoxide, and ethanol. Insoluble in ether, benzene and chloroform. |
存贮条件 | 储存温度 2-8℃ |
密度 | 1.6400 |
应用 | 5-Fluoro-2′-deoxyuridine has been used as a mitotic inhibitor in schwann cell proliferation, glia proliferation and nonneuronal cells in dorsal root ganglion cultures. |
产品介绍 | 5-Fluoro-2′-deoxyuridine, also called floxuridine elicits DNA-directed cytotoxicity in cancer cells. Floxuridine is effective for treating liver cancer and eliminating virulence of Staphylococcus aureus. Dipeptide prodrugs combination of floxuridine with gemcitabine are more cell permeable and display enhanced anti-proliferative activity. Floxuridine is effective on solid tumours and advanced stage cancers. |
生化机理 | Antineoplastic drug that acts as a potent inhibitor of thymidylate synthetase Resistance to FUdR can develop in cancer cell cultures, among other means, by low-level Mycoplasma infection. |
别名 | 5-氟-2'-脱氧尿苷 ;氟尿苷,氟脲脱氧核苷,氟苷,5-氟-2'-脱氧脲核苷;2′-Deoxy-5-fluorouridineFloxuridineFUDR1-(2-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil |
5-氟-2'-脱氧尿苷
5-Fluoro-2′-deoxyuridine (订货以英文为准)
编号:F110732
CAS号:50-91-9
分子式:C9H11FN2O5
分子量:246.19
产品名称 | 5-Fluoro-2′-deoxyuridine |
中文名称 | 5-氟-2'-脱氧尿苷 |
CAS号 | 50-91-9 |
MDL编码 | MFCD00006530 |
分子式(M.F.) | C9H11FN2O5 |
分子量(M.W.) | 246.19 |
储存条件 | 2-8°C储存 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg |
信号词 | Warning |
危害声明 | H302,H315,H319,H335 |
警示性声明 | P261,P305+P351+P338 |
个人防护设备 | dust mask type N95 (US), Eyeshields, Gloves |
WGK德国 | 3 |
风险声明 (欧洲) | R36/37/38;R22 |
安全声明(欧洲) | S26;S36 |
危害码(欧洲) | Xn |
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