MK-0752,γ-secretase(γ-分泌酶)抑制剂

MK-0752 (订货以英文为准)

编号:M126008
CAS号:471905-41-6
分子式:C21H21CLF2O4S
分子量:442.91
货号 品牌 包装 目录价 您的价格 库存 数量 购买
M126008-50mg 阿拉丁 50mg ¥5458.90
M126008-10mg 阿拉丁 10mg ¥2059.90
M126008-5mg 阿拉丁 5mg ¥1575.90
M126008-1mg 阿拉丁 1mg ¥427.90
M126008-100mg 阿拉丁 100mg ¥9826.90
M126008-25mg 阿拉丁 25mg ¥4119.90
产品名称 MK-0752
中文名称 MK-0752,γ-secretase(γ-分泌酶)抑制剂
CAS号 471905-41-6
分子式(M.F.) C21H21CLF2O4S
分子量(M.W.) 442.91
储存条件 -20°C储存
溶解性DMSO 89 mg/mL Water <1 mg/mL Ethanol 45 mg/mL
存贮条件储存温度-20°C
备注MK-0752 is a moderately potent γ-secretase inhibitor, which reduces Aβ40 production with IC50 of 5 nM. Phase 1/2.
生化机理MK-0752 is a potent gamma secretase (γ-secretase) inhibitor in clinical development with an IC50 of 5 nM for Aβ40 in human SH-SY5Y cells. MK-0752 is useful in treatment of Alzheimer’s disease
别名3-((1r,4s)-4-(4-chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)propanoic acid;3-((1r,4s)-4-(4-chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)propanoic acid
搜索质检报告(COA)
搜索MSDS
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