| 别名 | ; |
4,5-二氰-1,3-二硫酚-2-酮
4,5-Dicyano-1,3-dithiol-2-one （订货以英文为准）
编号：D155270
CAS号：934-31-6
分子式：C5N2OS2
分子量：168.19
| 产品名称 | 4,5-Dicyano-1,3-dithiol-2-one |
| 中文名称 | 4,5-二氰-1,3-二硫酚-2-酮 |
| CAS号 | 934-31-6 |
| MDL编码 | D155270 |
| 分子式（M.F.） | C5N2OS2 |
| 分子量（M.W.） | 168.19 |
| Reaxys-RN | 3612982 |
| 信号词 | Warning |
| 危害声明 | H315-H319-H335 |
| 警示性声明 | P261-P305 + P351 + P338 |
| 个人防护设备 | dust mask type N95 (US)， Eyeshields， Gloves |
| WGK德国 | 3 |
技术规格
| Background: | The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis. |
| Applications: | WB |
| Name of antibody: | FGFR4 |
| Immunogen: | Synthetic peptide of human FGFR4 |
| Full name: | fibroblast growth factor receptor 4 |
| Synonyms： | TKF; JTK2; CD334; MGC20292 |
| SwissProt: | P22455 |
| WB Predicted band size: | 88 kDa |
| WB Positive control: | Rat liver and Rat brain tissue |
| WB Recommended dilution: | 500-1000 |
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