Species
|
Gene ID
|
Accession
|
Source
|
Length
|
MW
|
Tag
|
Mouse
|
16963
|
P47993
|
E. coli
|
93aa
|
10.1kDa
|
-
|
About this Antibody
|
Name
|
Recombinant Murine Lymphotactin/XCL1 (Recombinant Murine Lymphotactin/XCL1; rMuLymphotactin/XCL1);Recombinant Mouse Lymphotactin/XCL1 ; 重组小鼠淋巴细胞趋化因子/XCL1
|
Synonyms
|
Lymphotactin; C motif chemokine 1; Cytokine SCM-1; Lymphotaxin; Small-inducible cytokine C1; Xcl1; Lptn; Ltn; Scyc1
|
Purity
|
>97% by SDS-PAGE and HPLC analyses.
|
Biological Activity
|
Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human XCR1 transfected murine BaF3 cells is less than 100ng/ml, corresponding to a specific activity of >1.0×104IU/mg.
|
Physical Appearance
|
Sterile Filtered White lyophilized (freeze-dried) powder.
|
Formulation
|
Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4.
|
Endotoxin
|
Less than 0.1EU/μg of rMuLymphotactin/XCL1 as determined by LAL method.
|
Reconstitution
|
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.
|
Category
|
Chemokines
|
Background
|
Chemokine (C motif) ligand (XCL1), as known as lymphotactin, is the only known member of the C-chemokine family and signals through the receptor XCR1, formally known as GPR5. The expression of lymphotactin is abundant in some activated T cells such as activated CD8+ T cells and other class I MHC restricted T cells. It is found in high levels in spleen, thymus, intestine and peripheral blood leukocytes, and at lower levels in lung, prostate gland and ovary. XCL1 induces its chemotactic function by binding to a chemokine receptor called XCR1. Recombinant Murine XCL1 which is a single non-glycosylated polypeptide chains containing 93 amino acids and it shares approximately 60% and 82% amino acid sequence homology with the human and rat XCL1.
|
Amino Acid Sequence
|
VGTEVLEESS CVNLQTQRLP VQKIKTYIIW EGAMRAVIFV TKRGLKICAD PEAKWVKAAI KTVDGRASTR KNMAETVPTG AQRSTSTAIT LTG
|
包装清单:
产品编号
|
产品名称
|
包装
|
P6764-5μg
|
Recombinant Murine Lymphotactin/XCL1
|
5μg
|
P6764-20μg
|
Recombinant Murine Lymphotactin/XCL1
|
20μg
|
P6764-100μg
|
Recombinant Murine Lymphotactin/XCL1
|
100μg
|
P6764-1mg
|
Recombinant Murine Lymphotactin/XCL1
|
1mg
|
-
|
说明书
|
1份
|
保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。