| 沸点 | 164°C |
| 熔点 | -121 °C |
| 密度 | 0.8600 |
| 别名 | 1,3-二氨基戊烷; 1,3-戊二胺;1,3-Pentanediamine; 1,3-Diaminopentane; |
1,3-二氨基戊烷
1,3-Diaminopentane （订货以英文为准）
编号：D155073
CAS号：589-37-7
分子式：C5H14N2
分子量：102.18
| 产品名称 | 1,3-Diaminopentane |
| 中文名称 | 1,3-二氨基戊烷 |
| CAS号 | 589-37-7 |
| 分子式（M.F.） | C5H14N2 |
| 分子量（M.W.） | 102.18 |
| 储存条件 | 充氩 |
| Reaxys-RN | 3246583 |
| 信号词 | Warning |
| 危害声明 | H315-H319-H335 |
| 警示性声明 | P261-P305 + P351 + P338 |
| 个人防护设备 | dust mask type N95 (US)， Eyeshields， Gloves |
| WGK德国 | 3 |
| 闪点（摄氏） | 113°C |
技术规格
| Background: | Calcium-activated and phospholipid-dependent serine/threonine-protein kinase involved in various processes such as regulation of the B-cell receptor (BCR) signalosome, apoptosis and transcription regulation. Plays a key role in B-cell activation and function by regulating BCR-induced NF-kappa-B activation and B-cell suvival. Required for recruitment and activation of the IKK kinase to lipid rafts and mediates phosphorylation of CARD11/CARMA1 at 'Ser-559', 'Ser-644' and 'Ser-652', leading to activate the NF-kappa-B signaling. Involved in apoptosis following oxidative damage: in case of oxidative conditions, specifically phosphorylates 'Ser-36' of isoform p66Shc of SHC1, leading to mitochondrial accumulation of p66Shc, where p66Shc acts as a reactive oxygen species producer. Acts as a coactivator of androgen receptor (ANDR)-dependent transcription, by being recruited to ANDR target genes and specifically mediating phosphorylation of 'Thr-6' of histone H3 (H3T6ph), a specific tag for epigenetic transcriptional activation that prevents demethylation of histone H3 'Lys-4' (H3K4me) by LSD1/KDM1A. Also involved in triglyceride homeostasis. Serves as the receptor for phorbol esters, a class of tumor promoters. |
| Applications: | WB, IHC, IF |
| Name of antibody: | PRKCB (Phospho-Thr641) |
| Immunogen: | Synthetic peptide of human PRKCB (Phospho-Thr641) |
| Full name: | protein kinase C, beta (Phospho-Thr641) |
| Synonyms： | PKCB; PRKCB1; PRKCB2; PKC-beta |
| SwissProt: | P05771 |
| IHC positive control: | Human lung carcinoma |
| IHC Recommend dilution: | 50-100 |
| WB Predicted band size: | 82 kDa |
| WB Positive control: | Jurkat cells untreated or treated with PMA |
| WB Recommended dilution: | 500-1000 |
| IF Positive control: | MCF7 cells |
| IF Recommended dilution | 100-200 |
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