| 溶解性 | Soluble in DMSO (>2 mg/ml), water (partly), 100% ethanol, and 83% methanol |
| 存贮条件 | 储存温度-20°C |
| 应用 | A cell permeable compound which stabilizes pre-formed actin filaments and inhibits their disassembly. |
| 生化机理 | Jasplakinolide is an actin-specific reagent that promotes actin polymerization and stabilizes actin filaments. In vitro, Jasplakinolidet potently induces actin polymerization by stimulating actin filament nucleation and competes with phalloidin for actin binding (Kd = 15 nM). In vivo, Jasplakinolide has been found to disrupt actin filaments and induce polymerization of monomeric actin into amorphous masses, the exact mechanism of which has not been determined yet. Jasplakinolide differs from other actin stabilizers in that it is cell permeable. This peptide has fungicidal, insecticidal and antiproliferative activity, and is useful for investigating cell processes mediated by actin polymerization and depolymerization, such as cell adhesion, locomotion, endocytosis, and vesicle sorting and release. |
| 别名 | ;Jaspamide |
茉莉花内酯
Jasplakinolide （订货以英文为准）
编号：J132593
CAS号：102396-24-7
分子式：C36H45BRN4O6
分子量：709.67
| 产品名称 | Jasplakinolide |
| 中文名称 | 茉莉花内酯 |
| CAS号 | 102396-24-7 |
| 分子式（M.F.） | C36H45BRN4O6 |
| 分子量（M.W.） | 709.67 |
| 储存条件 | 避光;-20°C储存 |
| 个人防护设备 | Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter |
| WGK德国 | 3 |
| 安全声明（欧洲） | 22,24/25 |
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