溶解性 | Soluble in water (partly), ethanol (4%), methanol (4%), DMF, and DMSO. |
存贮条件 | 储存温度-20°C |
密度 | 1.2600 |
应用 | A bacteriostatic inhibitor of translation at the 50S ribosome |
产品介绍 | Ostreogrycin A, also known as Virginiamycin M1, is a streptogramin macrolide antibiotic. Ostreogrycin A interacts with the bacterial 50S ribosome, inhibiting its function in a reversible manner. Activity of Ostreogrycin A at the ribosome blocks translation and produces a bacteriostatic effect. With addition of Virginiamycin S1 , the two antibiotics produce a synergistic bacteriocidal effect. The combination of these compounds, available as a Virginimycin complex , demonstrate efficacy against a broad range of bacteria. |
生化机理 | Virginiamycin M1 inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. It inactivates the 50S ribosome. S. virginiae inactivates VM1 by reducing its 16-carbonyl group, forming 16R-dihydroVM1. VM1 reductase participates solely in VM1 inactivation in vivo |
别名 | 春霉素 A;Mikamycin A;Staphylomycin |
蛎灰菌素A
Virginiamycin M1 (订货以英文为准)
编号:V102390
CAS号:21411-53-0
分子式:C28H35N3O7
分子量:525.59
货号 | 品牌 | 包装 | 目录价 | 您的价格 | 库存 | 数量 | 购买 |
---|---|---|---|---|---|---|---|
V102390-5mg | 阿拉丁 | 5mg | ¥4634.90 |
|
产品名称 | Virginiamycin M1 |
中文名称 | 蛎灰菌素A |
CAS号 | 21411-53-0 |
MDL编码 | MFCD00869411 |
分子式(M.F.) | C28H35N3O7 |
分子量(M.W.) | 525.59 |
储存条件 | -20°C储存 |
个人防护设备 | Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter |
WGK德国 | 3 |
安全声明(欧洲) | 22,24/25 |
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