| 沸点 | 157°C/4mmHg |
| 熔点 | 75-78℃ |
| 溶解性 | Soluble in ethanol (25 mg/ml), chloroform (1:1), ether (1:2), acetone (1:1.5), aqueous solutions of alkali hydroxides and carbonates, dichloromethane, methanol (50 mg/ml), and ethyl acetate. Insoluble in water. |
| 应用 | Ibuprofen 是 COX-1 和 COX-2 的抑制剂，IC50 值分别为 13 μM 和 370 μM，具有抗炎的活性。 |
| 产品介绍 | Ibuprofen inhibits Cox (cyclooxygenase) selectively, targeting Cox-1 (PGH synthase-1) with an IC50 of 13 μM, and Cox-2 (PGH synthase-2) with an IC50 of 370 μM. Ibuprofen is useful as a nonsteroidal anti-inflammatory research chemical. Ibuprofen is reported to inhibit the netrophil-dependent edema response of rabbit skin to C5a/PGE23. |
| 备注 | Ibuprofen (Advil, Dolgesic) is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively. |
| 生化机理 | 环加氧酶 (COX) 抑制剂，对 COX-1 的抑制活性大于对 COX-2 的抑制活性。 |
| 别名 | 2-(4-异丁基苯基)丙酸;4-异丁基-α-甲基苯乙酸;布洛芬;α-甲基-4-(异丁基)苯乙酸;(±)-2-(4-异丁基苯基)丙酸 ;4-Isobutyl-α-methylphenylacetic Acid;2-(4-Isobutylphenyl)propionic Acid;α-Methyl-4-(isobutyl)phenylacetic acid;(±)?-?2-?(4-?Isobutylphenyl)?propanoic acid |
布洛芬
Ibuprofen （订货以英文为准）
编号：I129291
CAS号：15687-27-1
分子式：C13H18O2
分子量：206.28
| 产品名称 | Ibuprofen |
| 中文名称 | 布洛芬 |
| CAS号 | 15687-27-1 |
| 分子式（M.F.） | C13H18O2 |
| 分子量（M.W.） | 206.28 |
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