熔点 | 223-224°C |
敏感性 | 对热敏感 |
存贮条件 | 储存温度 2-8°C |
密度 | 1.5920 |
应用 | 泻药/泻剂化合物;内源性乙酰胆碱的释放增加了肠道平滑肌收缩。遗传毒性和致突变性似乎是由芦荟大黄素由于抑制拓扑异构酶II活性 |
产品介绍 | 易溶于热乙醇,在苯及乙醚中呈黄色,在氨水和硫酸中呈绯红色,属蒽醌类化合物,在酸性溶液中被还原则生成蒽酚及其互变异构体的蒽酮。 |
生化机理 | Laxative/cathartic compound; increases the contraction of intestinal smooth muscle by releasing endogenous acetylcholine. Anti-tumor activity is associated with an increased production of reactive oxygen species (ROS) that, in turn, reduces the mitochondrial transmembrane electrical potential, thus inducing a permeability transition that sets in motion a series of events culminating in cellular apoptosis. Genotoxicity and mutagenicity appear to be due to the inhibition of topoisomerase II activity by aloe emodin. |
别名 | 1,8-二羟基-3-羟甲基蒽醌;芦荟泻素1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone;3-Hydroxymethylchrysazine |
芦荟大黄素
Aloe-emodin (订货以英文为准)
编号:A111278
CAS号:481-72-1
分子式:C15H10O5
分子量:270.24
产品名称 | Aloe-emodin |
中文名称 | 芦荟大黄素 |
CAS号 | 481-72-1 |
MDL编码 | MFCD00017373 |
分子式(M.F.) | C15H10O5 |
分子量(M.W.) | 270.24 |
储存条件 | 2-8°C储存 |
Reaxys-RN | 2044769 |
RTECS | DP0657000 |
闪点(摄氏) | >110 °C |
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