溶解性 | DMSO 74 mg/mL Water <1 mg/mL Ethanol 6 mg/mL |
存贮条件 | 储存温度2-8℃ |
应用 | 三磷酸二酯酶(PDE 3)抑制剂,.抗血栓形成和强心剂 |
产品介绍 | Cilastazol is a 2-oxo-quinoline with vasodilator, antimitogenic, antithrombotic, and cardiotonic properties. This compound has been shown to cause inhibition of adenosine uptake, eventually resulting in changes to cAMP levels. Studies have shown Cilostazol to be a potent inhibitor of PDE3A (phosphodiesterase 3A) in the cardiovascular system. In addition Cilastazol has also been observed to inhibit mitogenesis, migration of vascular smooth muscle cells, and platelet aggregation. Cilostazol displays a capacity to lower levels of serum triglycerides and cause some increase in HDL-cholesterol levels. |
备注 | Cilostazol is a potent cyclic nucleotide phosphodiesterase type 3 (PDE3) inhibitor with IC50 of 0.2 μM and inhibitor of adenosine uptake. |
别名 | 6-[4-(1-环己基-1H-四唑-5-基)丁氧基]-3,4-二氢-2(1H)-喹啉酮;6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-2(1H)-quinolinone; OPC 13013; OPC 21; Pletaal |
西洛他唑
Cilostazol (订货以英文为准)
编号:C129678
CAS号:73963-72-1
分子式:C20H27N5O2
分子量:369.46
产品名称 | Cilostazol |
中文名称 | 西洛他唑 |
CAS号 | 73963-72-1 |
MDL编码 | MFCD00866780 |
分子式(M.F.) | C20H27N5O2 |
分子量(M.W.) | 369.46 |
储存条件 | 2-8°C储存 |
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