西洛他唑

Cilostazol (订货以英文为准)

编号:C129678
CAS号:73963-72-1
分子式:C20H27N5O2
分子量:369.46
货号 品牌 包装 目录价 您的价格 库存 数量 购买
C129678-1g 阿拉丁 1g ¥60.90
C129678-250mg 阿拉丁 250mg ¥38.90
C129678-5g 阿拉丁 5g ¥99.90
产品名称 Cilostazol
中文名称 西洛他唑
CAS号 73963-72-1
MDL编码 MFCD00866780
分子式(M.F.) C20H27N5O2
分子量(M.W.) 369.46
储存条件 2-8°C储存
溶解性DMSO 74 mg/mL Water <1 mg/mL Ethanol 6 mg/mL
存贮条件储存温度2-8℃
应用三磷酸二酯酶(PDE 3)抑制剂,.抗血栓形成和强心剂
产品介绍Cilastazol is a 2-oxo-quinoline with vasodilator, antimitogenic, antithrombotic, and cardiotonic properties. This compound has been shown to cause inhibition of adenosine uptake, eventually resulting in changes to cAMP levels. Studies have shown Cilostazol to be a potent inhibitor of PDE3A (phosphodiesterase 3A) in the cardiovascular system. In addition Cilastazol has also been observed to inhibit mitogenesis, migration of vascular smooth muscle cells, and platelet aggregation. Cilostazol displays a capacity to lower levels of serum triglycerides and cause some increase in HDL-cholesterol levels.
备注Cilostazol is a potent cyclic nucleotide phosphodiesterase type 3 (PDE3) inhibitor with IC50 of 0.2 μM and inhibitor of adenosine uptake.
别名6-[4-(1-环己基-1H-四唑-5-基)丁氧基]-3,4-二氢-2(1H)-喹啉酮;6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-2(1H)-quinolinone; OPC 13013; OPC 21; Pletaal
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