| 溶解性 | DMSO ≥45mg/mL Water <1.2mg/mL Ethanol <1.2.mg/mL |
| 存贮条件 | 储存温度2-8℃ |
| 应用 | A potent PARP-1/-2 inhibitor shown to potentiate DNA damaging agents |
| 产品介绍 | Veliparib is a potent PARP-1/-2 inhibitor shown to potentiate DNA damaging agents. The ability to potentiate temozolomide (TMZ) and develop a biological marker for PARP inhibition. |
| 备注 | Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM, respectively. It is inactive to SIRT2. Phase 1/2. |
| 生化机理 | Veliparib is a potent inhibitor of both PARP-1 and PARP-2 by [3H]NAD+ with Kis of 5.2 and 2.9 nmol/L, respectively. |
| 别名 | ABT-888;PARP抑制剂;ABT-888; 2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-7-carboxamide |
Veliparib,PARP抑制剂
Veliparib （订货以英文为准）
编号：V127105
CAS号：912444-00-9
分子式：C13H16N4O
分子量：244.30
| 产品名称 | Veliparib |
| 中文名称 | Veliparib,PARP抑制剂 |
| CAS号 | 912444-00-9 |
| 分子式（M.F.） | C13H16N4O |
| 分子量（M.W.） | 244.30 |
| 储存条件 | 2-8°C储存 |
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