MBX-2982

MBX-2982 (订货以英文为准)

编号:M127623
CAS号:1037792-44-1
分子式:C22H24N8OS
分子量:448.54
货号 品牌 包装 目录价 您的价格 库存 数量 购买
M127623-50mg 阿拉丁 50mg ¥2199.90
M127623-5mg 阿拉丁 5mg ¥514.90
M127623-10mg 阿拉丁 10mg ¥823.90
M127623-25mg 阿拉丁 25mg ¥1647.90
产品名称 MBX-2982
中文名称 MBX-2982
CAS号 1037792-44-1
分子式(M.F.) C22H24N8OS
分子量(M.W.) 448.54
储存条件 -20°C储存
溶解性DMSO
存贮条件储存温度-20°C
产品介绍MBX-2982是口服活性GPR119选择性激动剂。
生化机理MBX-2982 is a potential first-in-class treatment for type 2 diabetes that targets G protein-coupled receptor 119 (GPR119), a receptor that interacts with bioactive lipids known to stimulate glucose-dependent insulin secretion. Preclinical data indicate that MBX-2982 is a potent selective orally-active GPR119 agonist that functions through a unique dual mechanism of action. First, it acts directly on the beta cell to increase insulin secretion. In addition, MBX-2982 stimulates release of the incretin GLP-1 from the gut. This dual action is unique and may offer improved glucose homeostasis over existing diabetes therapies, with potential for weight loss and improved islet health.
别名MBX 2982;MBX2982;5-乙基-2-[4-[4-[[[4-(1H-四氮唑-1-基)苯基]氧基]甲基]噻唑-2-基]哌啶-1-基]嘧啶;MBX 2982;MBX2982;5-Ethyl-2-[4-[4-[[[4-(1H-tetrazol-1-yl)phenyl]oxy]methyl]thiazol-2-yl]piperidin-1-yl]pyrimidine
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