溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
产品介绍 | MBX-2982是口服活性GPR119选择性激动剂。 |
生化机理 | MBX-2982 is a potential first-in-class treatment for type 2 diabetes that targets G protein-coupled receptor 119 (GPR119), a receptor that interacts with bioactive lipids known to stimulate glucose-dependent insulin secretion. Preclinical data indicate that MBX-2982 is a potent selective orally-active GPR119 agonist that functions through a unique dual mechanism of action. First, it acts directly on the beta cell to increase insulin secretion. In addition, MBX-2982 stimulates release of the incretin GLP-1 from the gut. This dual action is unique and may offer improved glucose homeostasis over existing diabetes therapies, with potential for weight loss and improved islet health. |
别名 | MBX 2982;MBX2982;5-乙基-2-[4-[4-[[[4-(1H-四氮唑-1-基)苯基]氧基]甲基]噻唑-2-基]哌啶-1-基]嘧啶;MBX 2982;MBX2982;5-Ethyl-2-[4-[4-[[[4-(1H-tetrazol-1-yl)phenyl]oxy]methyl]thiazol-2-yl]piperidin-1-yl]pyrimidine |
MBX-2982
MBX-2982 (订货以英文为准)
编号:M127623
CAS号:1037792-44-1
分子式:C22H24N8OS
分子量:448.54
产品名称 | MBX-2982 |
中文名称 | MBX-2982 |
CAS号 | 1037792-44-1 |
分子式(M.F.) | C22H24N8OS |
分子量(M.W.) | 448.54 |
储存条件 | -20°C储存 |
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